Now science have discovered that human cells can directly sense and respond to sound waves. 

While ago I sent this post to this blog about Solfeggio frequencies:

Sound frequency is the future of medicine. 

https://bluelotus01.blogspot.com/2024/09/solfeggio-frequencies-binaural-beats.html

Some people are more sensitive to sounds, Solfeggio frequencies and spiritual energies than others. For example there was three persons in my house and I played Solfeggios to them. One of them said that how can you listen to this because he feels like he is inside space spiral which just continues to go on. Other person said exact same music that she feels like she is inside of some relaxing Spa. Some people however doesn't feel anything from Solfeggios but they usually are materialistic who doesn't have spiritual senses and knowing.

Everyone is experiencing sounds differentelly and in spiritual realms this has been known for years and now science is proving the same. However there is no point to prove spiritual matters to paranormal researches or scientist because usually it leads nowhere.

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Scientific research just published:

Researchers at Kyoto University have discovered that human cells can directly sense and respond to sound waves. In lab tests, cultured cells exposed to 94 decibels, lawnmower-level sound, showed genetic changes triggered by mechanosensitive proteins. Different cells reacted uniquely, revealing a hidden layer of acoustic biology. The finding could inspire sound-based therapies and reshape understanding of noise’s impact on health.

Researchers at Kyoto University have discovered that human cells directly sense and respond to sound waves by activating mechanosensitive proteins, which then trigger changes in gene expression and cellular behavior, such as inhibiting fat cell development. This cellular "acoustic biology" reveals that sound influences cells at a fundamental level, potentially offering new avenues for sound-based therapies and providing deeper insight into the effects of noise on health. 

Key Findings from the Research

Cellular Sensing of Sound:

Cells possess mechanisms to directly perceive sound waves, rather than solely relying on the ears and brain for sound perception. 

Mechanosensitive Proteins are Key:

These proteins act as receptors on the cell membrane, responding to the mechanical pressure of sound waves and converting it into cellular signals. 

Gene Expression Changes:

Exposure to sound can alter the activity of various genes, including those involved in cell migration, stress response, and the development of fat cells. 

Specific Cell Responses:

Different types of cells exhibit unique reactions to sound, with some showing more pronounced effects than others. 

Novel Cellular Mechanisms:

The study identified that sound can influence cellular processes through both transcriptional control and RNA degradation, affecting how much protein a cell produces. 

Transitory and Specific Effects:

The alterations in gene expression are often temporary, and different gene responses can be triggered by varying sound frequencies, intensities, and wave forms. 

Implications of the Discovery

New Therapeutic Tools:

The non-invasive nature of sound makes it a promising tool for manipulating cellular functions, which could lead to new treatments for diseases like metabolic disorders or obesity. 

Understanding Noise-Related Health Impacts:

This research provides a new perspective on how environmental noise might affect human health by influencing cellular processes. 

Fundamental Biological Insight:

The findings highlight a previously unrecognized relationship between sound and life, suggesting that cells have evolved to physiologically react to the ever-present sounds of the world around them. 

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https://www.kyoto-u.ac.jp/en/research-news/2025-04-17

Kyoto, Japan -- There's a sensation that you experience -- near a plane taking off or a speaker bank at a concert -- from a sound so total that you feel it in your very being. When this happens, not only do your brain and ears perceive it, but your cells may also.

Technically speaking, sound is a simple phenomenon, consisting of compressional mechanical waves transmitted through substances, which exists universally in the non-equilibrated material world. Sound is also a vital source of environmental information for living beings, while its capacity to induce physiological responses at the cell level is only just beginning to be understood.

Following on previous work from 2018, a team of researchers at Kyoto University have been inspired by research in mechanobiology and body-conducted sound -- the sound environment in body tissues -- indicating that acoustic pressure transmitted by sound may be sufficient to induce cellular responses.

"To investigate the effect of sound on cellular activities, we designed a system to bathe cultured cells in acoustic waves," says corresponding author Masahiro Kumeta.

The team first attached a vibration transducer upside-down on a shelf. Then using a digital audio player connected to an amplifier, they sent sound signals through the transducer to a diaphragm attached to a cell culture dish. This allowed the researchers to emit acoustic pressure within the range of physiological sound to cultured cells.

Following this experiment, the researchers analyzed the effect of sound on cells using RNA-sequencing, microscopy, and other methods. Their results revealed cell-level responses to the audible range of acoustic stimulation.

In particular, the team noticed the significant effect of sound in suppressing adipocyte differentiation, the process by which preadipocytes transform into fat cells, unveiling the possibility of utilizing acoustics to control cell and tissue states.

"Since sound is non-material, acoustic stimulation is a tool that is non-invasive, safe, and immediate, and will likely benefit medicine and healthcare," says Kumeta.

The research team also identified about 190 sound-sensitive genes, noted the effect of sound in controlling cell adhesion activity, and observed the subcellular mechanism through which sound signals are transmitted.

In addition to providing compelling evidence of the perception of sound at the cell level, this study also challenges the traditional concept of sound perception by living beings, which is that it is mediated by receptive organs like the brain. It turns out that your cells respond to sounds, too.